You can set taxes directly on Uplisting for any direct bookings as well as for HomeAway/VRBO (in pilot).
Property settings > Pricing > Taxes & Fees
Property rent tax
A % tax on the total rental price including extra charges and cleaning fees. Use this for VAT, GST and HST.
Fixed tax per reservation
A fixed amount added to each booking regardless of number of guests or length of stay
Fixed guest tax per-person, per-night
A fixed amount multiplied by the number of guests
Fixed nightly tax
A fixed amount multiplied by the number of nights (irrespective of number of guests)